Overview of Chosen Chemical Compounds and Intermediates

1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is an impurity linked to bortezomib, a proteasome inhibitor Utilized in the cure of numerous myeloma. Its synthesis or study is crucial for making sure the purity and security in the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor during the synthesis of abiraterone acetate, a drug Utilized in the treatment method of prostate cancer by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-10-1): A crucial compound within the synthesis of imatinib, a drug that targets particular types of most cancers, like Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats several cancers including breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): They're intermediates in the synthesis of gemcitabine, an anti-most cancers drug. Their study is crucial for optimizing the creation method and 4-(dimethylamino)- guaranteeing substantial purity.
Lapatinib Intermediate (CAS NO. 231278-84-5): Lapatinib is applied to treat breast most cancers, and these intermediates are associated with its output.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist Utilized in the remedy of breast cancer. Several intermediates assist in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-16-nine): This intermediate is Employed (7a in the synthesis of paclitaxel, a chemotherapy drug powerful in managing cancers including ovarian, breast, and lung most cancers.
three. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Employed in the remedy of colorectal cancer and little mobile lung most cancers.
3-Amino-1-hydroxyadamantane (CAS 702-82-nine): This compound is involved with the synthesis of adamantane derivatives, that have various apps, including antiviral Qualities.
Vildagliptin Intermediates: Used in the creation of vildagliptin, an oral drug for type 2 diabetic issues that inhibits the enzyme DPP-four to control blood sugar concentrations.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is involved in the synthesis of various gluconic acid derivatives, which might be Utilized in food items, pharmaceutical, and industrial apps.
Canagliflozin Intermediate 2: A precursor inside the synthesis of canagliflozin, a medication applied to control form two diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).

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